Ace Plus Tablet

✔️ Uses of Ace Plus Tablet

• Mild to Moderate fever and pain

✔️ How does Ace Plus Tablet work?

• Paracetamol works by interfering with the production of a chemical called prostaglandins, which is responsible for the fever, swelling, and sensation of pain. It also acts on the area of the brain, which is responsible for controlling body temperature.
• Caffeine is a CNS stimulant. It helps in relieving pain and helps in improving the effectiveness of Paracetamol.

✔️ Side Effects of Ace Plus Tablet

• Nausea Or Vomiting
• Allergic Skin Reaction
• Gastric / Mouth Ulcer
• Anemia
• Fatigue

✔️ Quick Suggestions:

• Ace Plus Tablet is an analgesic used to reduce pain like toothaches, headaches, migraines, period pain, sore throat, nerve pain, tooth extraction pain, and symptoms of sprains, muscle pains, joint swelling, and stiffness.
• This medicine should not be used for treating any other condition unless specified by the doctor.
• Ace Plus Tablets should not be used by a pregnant woman because they may affect the fetus adversely.
• Inform your doctor if you are planning on becoming pregnant and it is not recommended for breastfeeding women.
• Also, inform your doctor about all other medicines that you take and your complete medical history.
• Take one to two tablets not more frequently than every 4-6hrs or as directed by your doctor
• Do not take any medicine on your own without confirming with your doctor during treatment with Ace PlusTablet.
• Nervousness and Dizziness can occur as side effects of this medicine in some individuals. If side effects bother you, please inform your doctor.
• This medicine is not recommended for use in children less than 12 years of age.

✔️ Indication of Ace Plus Tablet

Ace Plus Tablet is a combination medicine for relieving fever and mild to moderate pain, including headaches, backaches, toothaches, arthritis, and dysmenorrhea. It is not suitable for children under 12 years old. Do not use this medicine for more than 3 days without medical advice.

✔️ Pharmacology

This is a combination of acetaminophen and caffeine. Paracetamol has analgesic and antipyretic properties, and its anti-inflammatory activity is weak. Caffeine is an alkaloid, a derivative of xanthine, similar to theophylline. Through the intermolecular association with paracetamol, caffeine increases the solubility and transmembrane permeability of paracetamol. In addition, caffeine increases the pain threshold and pain tolerance. Caffeine also has the inherent power to increase the tone of blood vessels in the brain, which provides another benefit for the treatment of migraines and headaches.

✔️ Dosage & Administration of Ace Plus

Adult dose: 1-2 tablets every 4-6 hours. Maximum dose: 8 tablets daily.

Child dose: Not recommended for children below 12 years.

✔️ Interaction

Drug interactions can indeed vary from person to person, and it is essential to consult a doctor or healthcare professional to check for possible interactions before starting any medication. Here are some important interactions to be aware of with Ace PlusTablet:

• Alcohol: Avoid consuming alcohol while taking this medicine as it may increase the risk of severe side effects, including gastrointestinal bleeding and other symptoms like dizziness, weakness, and nausea.
• Drug Interactions: Ace PlusTabletmay interact with various drugs like carbamazepine, phenytoin, ciprofloxacin, duloxetine, theophylline, and others. It is essential to inform your doctor about all the medications you are taking, including prescription drugs, over-the-counter medicines, and herbal supplements.
• Disease Interactions: Extreme caution is required in patients with alcoholism, cardiovascular disorders, liver disease, seizures, and peptic ulcer disease. Dose adjustments or alternative medications may be necessary based on the clinical condition.
• Lab Interactions: Ace PlusTablet may cause a false-positive result in the 5-HIAA urine test. Inform the doctor and lab technician about all the medications you are taking before undergoing any lab tests.

✔️ Contraindications

• If you are allergic to caffeine or paracetamol or any other ingredients of Ace PlusTablet
• If you are suffering from high blood pressure and any heart diseases
• If you have a history of anxiety
• If you are pregnant or breastfeeding women
• If your age is below 12 years
• If you are taking medicines for psychiatric diseases, anxiety, decongestants, and high blood pressure

✔️ Pregnancy & Lactation

Pregnant women should consult a doctor before taking acetaminophen and caffeine. You can take acetaminophen and caffeine while breastfeeding.

✔️ Precautions & Warnings

• Patients with liver or kidney failure: Paracetamol is primarily metabolized in the liver, and caffeine can also affect liver function. In patients with liver or kidney failure, the clearance of these drugs from the body may be impaired, leading to potential accumulation and increased risk of adverse effects. It is essential to use these medications at lower doses and with close monitoring in such patients.
• Patients taking other hepatotoxic drugs: Hepatotoxic drugs are substances that can damage the liver. When taken with paracetamol and caffeine, which also have effects on the liver, there is an increased risk of liver damage. Patients taking other hepatotoxic drugs should use paracetamol and caffeine with caution and under medical supervision.
• Avoid using the drug for a long time without consulting a doctor: Both paracetamol and caffeine are safe when used at recommended doses for short-term relief of pain and fever. However, prolonged and excessive use of these medications can lead to adverse effects, especially on the liver and kidneys. It is essential to follow the recommended dosages and duration of use and seek medical advice if symptoms persist or worsen.

✔️ Storage Conditions

Store Ace PlusTablet below 25°C in a clean and dry place, protected from moisture, direct sunlight, and heat. Keep this medicine away from children and pets.